报告题目：Multiple phase CFD modeling for bio-processes
报告人：R. ERIC BERSON Associate Professor
Department of Chemical Engineering University of Louisville
R. ERIC BERSON
Department of Chemical Engineering
University of Louisville
Louisville, Kentucky 40292
Phone: (502) 852-1567 E-mail: email@example.com
Ph.D., University of Louisville, Chemical Engineering, 2000
M.S., University of Louisville, Chemical Engineering, 1995
B.S., Florida State University, Chemical Engineering, 1991
UNIVERSITY OF LOUISVILLE, Department of Chemical Engineering
Associate Professor, July 2011 - present
Assistant Professor, July 2005 - July 2011
Research Assistant Professor, August 2003 - July 2005
Carrier Vibrating Equipment, Louisville, KY, Project Manager, August 2001-July 2002
Waukesha Cherry-Burrell, Louisville, KY, Pilot Plant R&D Engineer, July 2000-August 2001.
Merck Pharmaceuticals, Albany, GA., Summer Internship, June 1990-August 1990.
Biofuels, Bio-reactor design, Computational fluid dynamics simulation
Subcontract from the University of Kentucky Research Foundation for NSF EPSCOR, Powering the Kentucky Bioeconomy for a Sustainable Future,~$500,000, Aug2014-Jul2019
Kentucky Science and Technology Corp., $75,000 Oct2011-Mar2013
National Renewable Energy Laboratory, Mixing of Lgno-Cellulosics in Stirred Tank Reactors， $76,828, Aug2010-Mar2012
Kentucky Renewable Energy Consortium, Production of Hig-Value Cellulase From Tobacco,
KY Governors Office of Energy Policy, Enzyme-free Hydrolysis of Kentucky Ag. Residues for
Conversion to Ethanol, $79,005, Oct200-3-Mar2009
KY Governors Office of Energy Policy, Kentucky Industrial Wood Wastes as a Renewable Energy
Resource, $135,855, Sep200-Aug2009
Subcontract from University of Kentucky Research Foundation, Evaluation of Collection, Storage, and Pretreatment of Corn Stover, $12,500, Jan200-Aug2007
Western Kentucky Consortium for Energy and the Environment, Conversion of Kentucky Wood
Residues to Ethanol, $94,461, Jan200-Jan2006
Department of Energy, Ethanol Production From Biomass: Large-Scale Facility Design, $295,000,
National Renewable Energy Laboratory, Reactor Design for Biorefineries Using Computational Fluid Dynamics, $126,000, Jul203-Feb2006
Authored one patent and more than 30 SCI papers in the field of biotechnology on internationally well-known journals such as Bioresource Technology, Biotechnology and Bioengineering, etc.
The goals of my research program have focused on the development and/or improvement of bio-‐processes where existing techniques are limited due to complexities with the working media, with emphasis on multiple phases and complex flow fields. Integrating computational fluid dynamics with experimental work provides an excellent tool for overcoming limitations when experimental observations or measurements are difficult or impractical. By experimentally validating certain conditions, the models can be extrapolated to other scenarios with a high degree of confidence. This provides a means for finding creative solutions to problems that otherwise could not be solved with the same level of detail and accuracy or could not be solved at all. Example applications to be presented here include characterization of fluid dynamics involving free surface flows between liquid and air, mixing quantification of chaotic flow of a high-‐solids slurry, determination of uniform suspension of solids in a solid-‐liquid mixture, and effect of scale and geometry on power requirements for a non-‐Newtonian slurry. The talk will also cover a discussion of confidence in modeling through use of computational mesh sensitivity analysis, monitoring relevant system properties, and experimental validation.
The talk will then focus on advancement of a new technique we developed for tracking mean age of individual phases independent of each other in multiphase flow systems. Preliminary results show very good validation for a system of two distinct liquid phases, although the technique is widely applicable to any combination of phases (liquids, solids, gases), and is especially advantageous for applications with extraordinary long residence times or ages. Many widespread applications are envisioned that would benefit from this such as: modeling pollution dispersion in the atmosphere; sedimentation in streams, rivers, lakes, and oceans; fluidized beds; and cardiovascular applications such as distinguishing between plasma and hematocrit flow through the heart, valves, stents, and other implantable medical devices.